• In general fish has a limited ability for

  2022-03-26

  

  In general, fish has a limited ability for digestion and metabolism of carbohydrate though carbohydrate is the cheapest dietary energy and carbon source to animals and the best candidate for replacing dietary protein (Enes et al., 2009, Kamalam et al., 2017, Wilson, 1994). Furthermore, the analysis

• br Conflict of interest br

  2022-03-26

  

  Conflict of interest Introduction Milk and dairy products are nutritious foods that provide lactose, calcium, phosphorous, magnesium and proteins, among other nutrients, which have been reported to have a fundamental role in bone development and healthy diets. An adequate consumption of dairy

• Crystal Violet br Introduction The fibroblast growth

  2022-03-26

  

  Introduction The fibroblast growth factor receptor (FGFR) pathway is an important oncogenic driver in malignant cancer. It controls cellular processes such as cell proliferation, differentiation, migration, Crystal Violet progression, metabolism, and survival. In non–small-cell lung cancer, the

• TRRAP participates in embryonic development as demonstrated

  2022-03-26

  

  TRRAP participates in embryonic development, as demonstrated by its binding with proteins regulating the Notch signaling pathway in fruit fly, the Ras signaling pathway in C. elegans, or the Wnt signaling pathway in 293T cells. Therefore we suspect that TRRAP variants, more especially those falling

• An azabicyclic compound named S a

  2022-03-26

  

  An azabicyclic Bay 11-7085 synthesis named S 38093, (4-[3-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)propoxy]benzamide), was introduced by Servier with H3R antagonist and inverse agonist activity (Sors et al., 2017). The compound contains all the drug-likeness criteria owing to its physico

• Annexin A ANXA a member of

  2022-03-26

  

  Annexin A7 (ANXA7), a member of annexin superfamily, is a Ca2+- and phospholipid-binding protein and possesses GTPase activity [5,6]. The ANXA7 gene is located on human chromosome 10q21, where multiple potential tumor suppressor genes exist. Homozygous ANXA7 (−/−) knockout mice showed a lethal pheno

• The ketone body receptor HCA is

  2022-03-25

  

  The ketone body receptor HCA2 is most likely not active under normal conditions, since local levels and plasma levels of ketone bodies such as β-HB are too low to activate the receptor. However, overnight fasting or prolonged starvation results in plasma levels of the ketone body in the millimolar r

• Naringin has been shown to have significant

  2022-03-25

  

  Naringin has been shown to have significant anti-inflammation, anti-oxidative stress, glucolipid metabolic regulation, and myocardial protection effects (Gopinath et al., 2011, Gopinath and Sudhandiran, 2012), suggesting that it may mitigate ADC by inhibiting P2X7 receptors. In the present study, na

• br The glycine transporter GlyT was originally identified

  2022-03-25

  

  The glycine transporter 1 (GlyT1) was originally identified as a member of the solute carrier family 6 of sodium- and chloride-dependent neurotransmitter transporters . GlyT1 is expressed in the central nervous system and in peripheral tissues; mainly in erythroid cells, from erythroblasts in the

• The current study also inferred that

  2022-03-25

  

  The current study also inferred that MT content in Crassostrea gigas might be associated with the Cd level, and can be affected by MT turnover. The rifadin of MT in cytosol is beneficial for aquatic organisms to adapt the seawater contaminated by heavy metals, and MT is a biomarker for marine inver

• Ubiquitination of GlyRs subunit on plasma membrane has

  2022-03-25

  

  Ubiquitination of GlyRs-α1 subunit on plasma membrane has been shown to initiate the receptor aa 629 sale and subsequent degradation in lysosomes (Buttner et al., 2001). However, the specific E3 ligase responsible for GlyRs-α1 ubiquitination is largely unknown as yet. Also, the functional consequen

• By regulation of synaptic glutamate concentration glutamate

  2022-03-25

  

  By regulation of synaptic glutamate concentration, glutamate transporters play an important role in limiting glutamate signaling and controlling the activation of glutamate receptors (Rimmele and Rosenberg, 2016). Reduced glutamate transport is thought to underlie the pathogenesis of numerous neurol

• In this study we investigated

  2022-03-25

  

  In this study, we investigated the contribution of GCK, G6PC, and PCK expression to glycemia in diabetes. We examined liver tissue from 40 obese subjects: 12 had normal glucose tolerance (NGT) and 28 had type 2 diabetes. Materials and methods Results Discussion This study aimed to investig

• While TUNEL staining is traditionally thought to

  2022-03-25

  

  While TUNEL staining is traditionally thought to be an apoptosis marker, studies have shown that TUNEL can stain necrotic jnk inhibitors [19], [20], [21]. Furthermore, DNA degradation has also been observed in necrotic cells [22]. TUNEL staining alone is therefore insufficient to distinguish apopto

• Introduction Human pathogenic Leishmania protozoa comprise d

  2022-03-25

  

  Introduction Human pathogenic Leishmania protozoa comprise 20 different species that are distributed throughout the world and cause the disease leishmaniasis [1]. Transmission primarily occurs through the bite of a female sand fly and clinical manifestations of the disease span from cutaneous lesio

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