• The use of FTAI can overcome the negative

  2022-12-01

  

  The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable n acetylneuraminic acid follicle. Pregnancy rates obtained with FTAI may be comparable or better than those

• We report here the first study on the inhibitory

  2022-12-01

  

  We report here the first study on the inhibitory effects of the organic nitrates – on human erythrocyte GR. The previous reports by Becker et al., investigated other nitro derivatives (including arylizoalloxazines) by using Beutler’s method, monitoring GR inhibition. Data of show inhibition of hGR

• br Materials and methods br Results br Discussion Diabetic k

  2022-12-01

  

  Materials and methods Results Discussion Diabetic kidney disease (DKD) is the most common cause of end-stage renal disease [15], [16]. The pathogenesis of DKD is not fully understood, and there is no effective treatment. Although previous studies suggested that early lesions of DKD are foun

• br Acknowledgments The authors thank Claudia Wittrock for he

  2022-12-01

  

  Acknowledgments The authors thank Claudia Wittrock for her excellent technical assistance. The work was supported by grants of the Deutsche Forschungsgemeinschaft (SFB974 TP B05) and of the Anton-Betz-Stiftung to N.K. A.M. is an associate member of the iBrain graduate school at the University of

• Antagonist G br Experimental procedures br Results

  2022-11-30

  

  Experimental procedures Results Discussion Acknowledgments Introduction β-Adrenergic receptors (β-ARs) belong to the superfamily of membrane proteins termed G protein-coupled receptors. β-ARs are distributed in the effector Antagonist G of most of the sympathetic nerve fibers, and th

• Interestingly our transgenic mouse model with macrophages ex

  2022-11-30

  

  Interestingly, our transgenic mouse model with macrophages expressing AdipoR1 showed not only improved insulin sensitivity and inflammation in skeletal muscle and adipose tissues, but fat mass, macrophage and plasma lipid accumulation and foam cell formation was also favorably reduced resulting from

• A review has recently been published to evaluate the

  2022-11-29

  

  A review has recently been published to evaluate the potential effects of food, alcohol and AR-M 1896 receptor juices on the pharmacokinetics and pharmacodynamics of the drugs for BPH. The authors reviewed the PubMed database during the years 1991–2015. In addition, a digital version of Stockley on

• The altered frequency of CD T

  2022-11-29

  

  The altered frequency of CD4+ T A 967079 in 5-LO−/− mice led us to hypothesize that these leukocytes could be exerting a primary control of the inflammatory response. In fact, the lack of 5-LO resulted in the accumulation of CD4+CD25+ cells expressing Treg markers. It is plausible to speculate that

• In the last decade the

  2022-11-29

  

  In the last decade, the zebrafish has emerged as a valuable vertebrate model to systematically dissect the genetic underpinnings of both vertebrate heart development and function [8,9], as well as distinct cardiac diseases such as congenital heart disease [10], cardiomyopathies [11,12] and cardiac a

• Echinocandin resistance is systematically associated

  2022-11-24

  

  Echinocandin resistance is systematically associated with point mutations in either FSK1 or FSK2 genes [7], [104]. These mutations are located in two different not spot regions of these genes named HS1 and HS2. Hot spot mutations have been reported in C. albicans, C. glabrata, C. tropicalis, C. krus

• br Acknowledgments The authors thank Claudia

  2022-11-24

  

  Acknowledgments The authors thank Claudia Wittrock for her excellent technical assistance. The work was supported by grants of the Deutsche Forschungsgemeinschaft (SFB974 TP B05) and of the Anton-Betz-Stiftung to N.K. A.M. is an associate member of the iBrain graduate school at the University of

• br Improvement of endothelial function The vascular endothel

  2022-11-18

  

  Improvement of endothelial function The vascular endothelium is a single layer of TH287 that lines the inner surface of all blood vessels and the heart. In addition to function as a selective barrier to prevent the diffusion of macromolecules from the blood lumen to the intestinal space, the vas

• 5-Formyl-UTP mg In this study significant reduction in

  2022-11-18

  

  In this study, significant reduction in the HCO3− content in sham-operated and testosterone-treated rats following bafilomycin A1 administration suggested that V-ATPase could be involved in mediating the decrease in vas deferens fluid HCO3− content, most probably due to the increase in H+ secretion

• phenylephrine hydrochloride synthesis br Materials and metho

  2022-11-18

  

  Materials and methods Results Discussion Many studies investigate the role of 12/15-LOX in cancer cell,23, 24, 25 however we here first found that host 12/15-LOX also plays an important role in metastasis progression. We have demonstrated that 12(S)-HETE increased melanoma cell adhesion to

• br Synthetic lethal approaches In addition to

  2022-11-18

  

  Synthetic lethal approaches In addition to the potential utility of ATM and ATR as chemo- or radiosensitisers, recent studies suggest that such compounds may have single agent activity in certain subsets of patients through induction of synthetic lethality. Two genes are considered synthetically

14323 records 319/955 page Previous Next First page 上5页 316317318319320 下5页 Last page